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Series GSE41792 Query DataSets for GSE41792
Status Public on Jun 26, 2013
Title Differential expression in Wn5a and vector transduced 4T1 cells. [RNA-Seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary A highly metastatic breast cancer cell line, 4T1, was used to generate stable Wnt5a expressing and vector only control cells. Cells were generated using lentivirus infection and selection with blasticidin. Expression of Wnt5a was confirmed using western blot. Cell behaviour was characterized. Wnt5a expressing cells exhibited reduced migration in a transwell assay and reduced metastasis in a tail vein injection assay. Growth was not significantly affected.
Overall design One sample of each condition.
Contributor(s) Serra R, Crossman D
Citation(s) 23484019
Submission date Oct 23, 2012
Last update date May 15, 2019
Contact name Rosa Serra
Phone 205-934-0842
Organization name University of Alabama at Birmingham
Department Cell Biology
Lab Serra
Street address 1918 University Blvd. 660 MCLM
City Birmingham
State/province AL
ZIP/Postal code 35294-0005
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (2)
GSM1024394 Vector 1 RNA-Seq
GSM1024395 Wnt5a 1 RNA-Seq
This SubSeries is part of SuperSeries:
GSE41793 Differential expression in Wn5a and vector transduced 4T1 cells.
BioProject PRJNA178237
SRA SRP016627

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41792_RAW.tar 1.1 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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