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Series GSE40726 Query DataSets for GSE40726
Status Public on Sep 13, 2012
Title Transcriptional profiling of IRF4 -/- vs IRF4 +/- T-cells under Th17 polarizing conditions
Organism Mus musculus
Experiment type Expression profiling by array
Summary Transcriptional profiling of T-cells isolated from spleen of IRF4 -/- mice and cultured under Th17 polarizing conditions for 42 hrs compared to cells similarly isolated and cultured from spleen of IRF4 +/- mice. The aim of the study was to identify global misexpression of genes in IRF4 -/- cells and hence identify key pathways regulated by IRF4 during Th17 differentiation.
Overall design Two-condition experiment, IRF4 -/- vs IRF4 +/- Th17 cells at 42hrs. Biological replicates: 3 for each condition
Contributor(s) Agrawal S, Singh H
Citation(s) 22983707
Submission date Sep 10, 2012
Last update date Jan 12, 2017
Contact name Smita Agrawal
Organization name Genentech Inc.
Department Immunology
Street address 1 DNA Way
City South San Francisco
State/province CA
ZIP/Postal code 94080
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (6)
GSM999794 IRF4-mut_Th17_cells_42hr_rep1
GSM999795 IRF4-mut_Th17_cells_42hr_rep2
GSM999796 IRF4-mut_Th17_cells_42hr_rep3
This SubSeries is part of SuperSeries:
GSE40483 A genomic regulatory element that directs assembly and function of immunespecific AP-1-IRF complexes
BioProject PRJNA174766

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40726_Analyzed_data.txt.gz 17.2 Kb (ftp)(http) TXT
GSE40726_RAW.tar 25.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
Processed data are available on Series record

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