|
Status |
Public on Jul 20, 2013 |
Title |
Overexpression of SChLAP1 versus LACZ in RWPE cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
SChLAP1 is a novel long non-coding RNA expressed in prostate cancer. Here we performed transcriptional profiling of the benign immortalized prostate cell line RWPE overexpressing two isoforms of the SChLAP-1 lncRNA compared with RWPE overexpressing LACZ. Our goal was to determine the effect of SChLAP1 overexpression on gene expression in prostate cells.
|
|
|
Overall design |
Two-condition experiment: RWPE overexpressing SChLAP1 versus RWPE overexpressing LACZ. Biological replicates: 1 control replicate, 2 experimental replicates. Technical replicates: 2 replicates per SChLAP1 isoform. Cell lines: RWPE.
|
|
|
Contributor(s) |
Jing X, Iyer MK, Prensner JR |
Citation(s) |
24076601 |
|
Submission date |
Aug 27, 2012 |
Last update date |
Feb 22, 2018 |
Contact name |
Matthew Iyer |
E-mail(s) |
mkiyer@med.umich.edu
|
Phone |
7346154503
|
Organization name |
University of Michigan
|
Department |
Michigan Center for Translational Pathology
|
Lab |
Chinnaiyan Lab
|
Street address |
5316 CCGC 0940 1400 E. Medical Center Drive
|
City |
Ann Arbor |
State/province |
MI |
ZIP/Postal code |
48109-0940 |
Country |
USA |
|
|
Platforms (1) |
GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
|
Samples (4)
|
|
This SubSeries is part of SuperSeries: |
GSE40386 |
SChLAP-1, a long non-coding RNA, antagonizes the SWI/SNF complex and coordinates aggressive prostate cancer. |
|
Relations |
BioProject |
PRJNA173822 |