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Series GSE40332 Query DataSets for GSE40332
Status Public on Feb 23, 2014
Title Gene expression profiles in wild-type and Jmjd3-/- embryos
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gene expression profiles were compared between wild-type and Jmjd3-/- embryos at E9.5 when mRNAs of posterior Hox genes are upregulated, because Jmjd3-/- mice embryos showed homeotic transformation. As expected, mRNAs of Hoxd10 and Hod11 were decreased in Jmjd3-/- embryos. Moreover, gene onthology (GO) analyses identified down-regulated genes (FC>1.5) in Jmjd3-/- embryos were “multicellular organismal development” and “developmental process”.
Overall design Gene expressions in wild-type and Jmjd3-/- posterior half of embryos at E9.5 were examined. Two independent RNA samples of each genotypes were used to verify the reproducibility of the microarray analyses.
Contributor(s) Naruse C, Shibata S, Abe K, Kawaguchi T, Kato T, Nishiuchi T, Asano M
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Submission date Aug 23, 2012
Last update date Jan 12, 2017
Contact name Takumi Nishiuchi
Organization name Kanazawa University
Street address 13-1 Takaramachi
City Kanazawa
ZIP/Postal code 920-0934
Country Japan
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (4)
GSM991395 1_RNA from posterior half of Jmjd3-/- embryo
GSM991396 3_RNA from posterior half of wild-type embryo
GSM991397 4_RNA from posterior half of wild-type embryo
BioProject PRJNA173547

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40332_RAW.tar 8.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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