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Series GSE3982 Query DataSets for GSE3982
Status Public on Jan 10, 2006
Title Human immune cell transcriptome
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In the present study we used Affymetrix oligonucleotide microarrays to produce gene transcription profiles for the major leukocyte types in humans. This comprehensive dataset enabled us to not only establish which genes were expressed in each leukocyte type, but also which genes were expressed in each subset after activation. The used of a comprehensive dataset of gene profiles from all the major human leukocyte subsets enabled a novel and powerful means for identification of genes associated with single leukocyte subsets, or different immune paradigms.
Keywords: Cell type comparison
 
Overall design Different leukocyte subsets were either isolated or differentiated from human blood to obtain consistently >95% pure populations. Gene profiles for activated effector cells such as macrophages, neutrophils and mast cells were also generated. In most cases, microarray analyses were perform on samples from 2 independent donors.
 
Contributor(s) Mackay CR, Jeffrey KL, Liu SM, Chtanova T, Sisavanh M, Newton R, Zimmer S
Citation(s) 16474395
Submission date Jan 06, 2006
Last update date Aug 10, 2018
Contact name Charles Reay Mackay
E-mail(s) c.mackay@garvan.org.au
Phone +61-2-92958405
Fax +61-2-92958404
Organization name Garvan Institute for Medical Research
Street address 384 Victoria St
City Darlinghurst
State/province NSW
ZIP/Postal code 2010
Country Australia
 
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (32)
GSM90660 Eosinophils_control_rep1
GSM90661 Eosinophils_PMA 2h_rep1
GSM90662 Cord blood-derived mast cells_control_rep1
Relations
BioProject PRJNA94247

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