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| Status |
Public on Dec 28, 2012 |
| Title |
Helicobacter pylori-mediated Epigenetic Dysregulation of FOXD3 Tumor-suppressive Cascade In Gastric Carcinogenesis [MMASS] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
Promoter hypermethylation occurs in human gastric cancers, but whether the deregulated genes contribute to the multi-step Helicobacter pylori (H pylori)-induced gastric carcinogenesis remains unclear. We used Microarray-based Methylation Assessment of Single Samples (MMASS) to identify differential methylated genes in 10 human gastric cancer tissues.
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| Overall design |
Two-condition experiment, gastric cancers from patients (n = 5 per group) who survived 5 years or more (long-term survivors group) and who died of disease prior to 5 years (short-term survivors group)
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| |
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| Contributor(s) |
Cheng AS |
| Citation(s) |
23058321 |
| |
| Submission date |
Jul 24, 2012 |
| Last update date |
Dec 28, 2012 |
| Contact name |
Alfred S Cheng |
| E-mail(s) |
alfredcheng@cuhk.edu.hk
|
| Organization name |
Institute of Digestive Disease, The Chinese University of Hong Kong
|
| Street address |
Rm 707, LiKaShing Medical Sciences Building, Prince of Wales Hospital, Shatin
|
| City |
Hong Kong |
| ZIP/Postal code |
852 |
| Country |
Hong Kong |
| |
|
| Platforms (1) |
| GPL2040 |
UHN Human CpG 12K Array (HCGI12K) |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE39600 |
Helicobacter pylori-mediated Epigenetic Dysregulation of FOXD3 Tumor-suppressive Cascade In Gastric Carcinogenesis |
|
| Relations |
| BioProject |
PRJNA171221 |
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