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Series GSE38824 Query DataSets for GSE38824
Status Public on Jan 24, 2013
Title Analysis of TF binding sites and histone modification in IRF8-induced monocyte differentiation
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Chromatins were prepared from myeloid progenitor cell line Tot2 cells transduced with retrovirus for control MSCV or MSCV-IRF8. Chromatin immunoprecipitation (ChIP) was carried out by using anti-IRF8 antibody, anti-PU.1 antibody or anti-histone H3K4me1 antibody.
ChIP-Seq peaks were identified using the FindPeaks tool in the HOMER package or SICER with input DNA tags as background distribution.
Potential IRF8-direct target genes were identified based on ChIP-Seq and the alteration of expression by IRF8-induction.
Overall design Examination of 2 transcription factor occupancy and 1 histone modifications in myeloid progenitor cells and monocyte-like cells differetiated by IRF8 expression
Contributor(s) Nishiyama A, Tamura T
Citation(s) 23319570
Submission date Jun 20, 2012
Last update date May 15, 2019
Contact name Tomohiko Tamura
Organization name Yokohama City University
Department Department of Immunology
Street address 3-9 Fukuura, Kanazawa-ku
City Yokohama
ZIP/Postal code 236-0004
Country Japan
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (6)
GSM950321 Tot2, MSCV, Day3, input DNA
GSM950322 Tot2, MSCV, Day3, anti-H3K4me1
GSM950323 Tot2, MSCV-IRF8, Day3, input DNA
This SubSeries is part of SuperSeries:
GSE38825 IRF8-induced monocyte differentiation
BioProject PRJNA169037
SRA SRP013833

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE38824_RAW.tar 402.6 Mb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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