|
| Status |
Public on Jun 14, 2012 |
| Title |
Gene expression in human germinal center light zone and dark zone B cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Microarrays of gene expression in human germinal center light zone and dark zone B cells sorted according to the expression of cell surface molecules CD83 and CXCR4
We used microarray data to identify genes differentially expressed by B cells in the light and dark zones of germinal centers from human tonsil specimens.
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| Overall design |
Germinal center B cells (CD19+CD38+IgD-) were sorted from pediatric tonsil discard specimens into light zone (CXCR4hi/CD83lo) and dark zone (CXCR4lo/CD83hi) populations, from which RNA was extracted
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| |
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| Contributor(s) |
Victora GD, Dominiguez-Sola D, Dalla-Favera R, Nussenzweig MC |
| Citation(s) |
22740445 |
| |
| Submission date |
Jun 13, 2012 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Gabriel D Victora |
| E-mail(s) |
victora@wi.mit.edu
|
| Organization name |
Whitehead Institute
|
| Street address |
9 Cambridge Center
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (8)
|
| GSM947665 |
human light zone, biological replicate 1 |
| GSM947666 |
human light zone, biological replicate 2 |
| GSM947667 |
human light zone, biological replicate 3 |
| GSM947668 |
human light zone, biological replicate 4 |
| GSM947669 |
human dark zone, biological replicate 1 |
| GSM947670 |
human dark zone, biological replicate 2 |
| GSM947671 |
human dark zone, biological replicate 3 |
| GSM947672 |
human dark zone, biological replicate 4 |
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| This SubSeries is part of SuperSeries: |
| GSE38712 |
Gene expression in germinal center light zone and dark zone B cells |
|
| Relations |
| BioProject |
PRJNA168511 |
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