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| Status |
Public on Dec 03, 2012 |
| Title |
Expression data from AK4 overexpression in CL1-0 lung cancer cell line and AK4 knockdown in CL1-5 lung cancer cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We demonstrate that AK4 down-regulation shRNAs significantly reduced cell migration and invasion in highly invasive lung cancer cell lines in vitro, as well as in lung metastases in vivo
We used microarrays to analyze the AK4 regulated gene expression underlying invasion-metastasis cascade.
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| |
|
| Overall design |
CL1-0 lung adenocarcinoma cells with AK4 overexpression and CL1-5 cells with AK4 knockdown were selected for RNA extraction and hybridization on Affymetrix microarrays.
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| |
|
| Contributor(s) |
Jan Y, Hsiao M |
| Citation(s) |
23002211 |
| |
| Submission date |
May 10, 2012 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Michael Hsiao |
| E-mail(s) |
mhsiao@gate.sinica.edu.tw
|
| Phone |
886-2-27898752
|
| Organization name |
Academia Sinica
|
| Department |
Genomics Research Center
|
| Lab |
Michael Hsiao Lab
|
| Street address |
128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan
|
| City |
Taipei |
| ZIP/Postal code |
115 |
| Country |
Taiwan |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (4)
|
| GSM929690 |
CL1-0 cell line expressing control vector |
| GSM929691 |
CL1-0 cell line expressing AK4 |
| GSM929692 |
CL1-5 cell line expressing Non-silencing shRNA vector |
| GSM929693 |
CL1-5 cell line expressing AK4 shRNA vector |
|
| Relations |
| BioProject |
PRJNA165139 |
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