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Series GSE37393 Query DataSets for GSE37393
Status Public on Jan 01, 2013
Title Daily cycling of genome-wide histone methylation
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Daily (circadian) clocks are essential for regulating and coordinating physiology in mammals. Modulation of local chromatin structure has been shown for only a small number of genes, principally thought to be directly modulated by Clock-mediated histone acetylation. Here we show that genome-wide changes of active and suppressive histone marks control global chromatin architecture over the day and night.
Overall design Examination of mouse liver tissue at 4 time-points around the clock in "free-running", continuous conditions (constant darkness, temperature and food available ad libitum).
Contributor(s) Valekunja UK, Reddy AB
Citation(s) 23297224
Submission date Apr 18, 2012
Last update date May 15, 2019
Contact name Utham Kashyap Valekunja
Organization name Smilow Center for Translational Research
Department Department of Systems Pharmacology & Therapeutics, Perelman School of Medicine, University of Pennsylvania
Street address 10-179/180 Lab, 3400 Civic Center Boulevard, Building 421
City Philadelphia
ZIP/Postal code PA 19104
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (20)
GSM917517 Mll3_CT0_ChIPSeq
GSM917518 Mll3_CT6_ChIPSeq
GSM917519 Mll3_CT12_ChIPSeq
This SubSeries is part of SuperSeries:
GSE37396 The histone methyltransferase MLL3 regulates genome-scale circadian transcription
SRA SRP012311
BioProject PRJNA159825

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37393_RAW.tar 10.8 Gb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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