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Series GSE37228 Query DataSets for GSE37228
Status Public on Oct 12, 2014
Title miR-155 promotes Th17 development by targeting Jarid2
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Genome-wide analysis was performed on microRNA 155+/+ and -/- Th17 cells to determine the differentially expressed transcripts that are regulated by miR-155. We found that Jarid2 was differentially expressed in absence of miR-155 and highlight the mechanism for the silencing of IL-22 by Jarid2 and PRC2 in miR-155-/- Th17 cells.
Overall design Comparison of transcriptome of Th17 cells in presence or absence of microRNA 155
Contributor(s) Escobar T, Burr P, Nguyen CK, Muljo SA
Citation(s) 24856900
Submission date Apr 12, 2012
Last update date May 15, 2019
Contact name Gokhul Krishna Kilaru
Phone 214-648-4158
Organization name University of Texas Southwestern Medical Center
Department Department of Neuroscience
Lab Joseph S. Takahashi
Street address 6000 Harry Hines Boulevard
City Dallas
State/province TEXAS
ZIP/Postal code 75390
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (2)
GSM914079 miR-155+/+ Th17
GSM914080 miR-155-/- Th17
BioProject PRJNA158955
SRA SRP012170

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Supplementary file Size Download File type/resource
GSE37228_RAW.tar 149.7 Mb (http)(custom) TAR (of BEDGRAPH)
GSE37228_countData.txt.gz 205.8 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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