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| Status |
Public on Oct 12, 2014 |
| Title |
miR-155 promotes Th17 development by targeting Jarid2 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Genome-wide analysis was performed on microRNA 155+/+ and -/- Th17 cells to determine the differentially expressed transcripts that are regulated by miR-155. We found that Jarid2 was differentially expressed in absence of miR-155 and highlight the mechanism for the silencing of IL-22 by Jarid2 and PRC2 in miR-155-/- Th17 cells.
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| |
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| Overall design |
Comparison of transcriptome of Th17 cells in presence or absence of microRNA 155
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| |
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| Contributor(s) |
Escobar T, Burr P, Nguyen CK, Muljo SA |
| Citation(s) |
24856900 |
| Submission date |
Apr 12, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Gokhul Krishna Kilaru |
| E-mail(s) |
gokhul.kilaru@utsouthwestern.edu
|
| Phone |
214-648-4158
|
| Organization name |
University of Texas Southwestern Medical Center
|
| Department |
Department of Neuroscience
|
| Lab |
Joseph S. Takahashi
|
| Street address |
6000 Harry Hines Boulevard
|
| City |
Dallas |
| State/province |
TEXAS |
| ZIP/Postal code |
75390 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
|
| Samples (2) |
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| Relations |
| BioProject |
PRJNA158955 |
| SRA |
SRP012170 |
