|
| Status |
Public on Apr 12, 2012 |
| Title |
Microarray analyses for wild type and Mof knockout murine ES cells. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We report the application of Affy based microarray technology for profiling of gene expression in mouse embryonic stem cells with or without histone acetytransferase MOF. We find that Mof regulates a wide range of genes in mouse ESCs including those important for ESC pluripotency and ESC differentiation. Mof deletion leads to similar number of genes that are up or down regulated. This study provides a framework for understanding the function of Mof in regulating ESC core transcription network.
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| Overall design |
Compare gene expression difference in two cell lines
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| |
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| Contributor(s) |
Dou Y, Li X, Pandey R, Qin Z, Li L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 09, 2012 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Yali Dou |
| Organization name |
University of Michigan
|
| Department |
Department of Pathology, Department of Biological Chemistry
|
| Lab |
Dou
|
| Street address |
Rm 5215A, MS I, 1301 Catherine Rd,
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA158985 |
