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Series GSE36879 Query DataSets for GSE36879
Status Public on Feb 25, 2013
Title Profiling A375P melanoma cells following PGC1a suppression
Organism Homo sapiens
Experiment type Expression profiling by array
Summary PGC1a is a transcriptional coactivator that regulates energy metabolism. PGC1a is highly expressed in a subset of melanoma tumors and cell lines. We generated gene-expression profile of control and PGC1alpha depleted A375P melanoma cells, a melanoma cell line that expresses very high levels of PGC1a to investigate the role of this gene in melanoma.
Overall design Lentivirus were used to generate stable cell lines expressing two shRNAs against PGC1alpha or two shRNAs controls. Cells were selected with purmycin for 48h and RNA was harvested 48h after selection and gene-expression arrays were generated.
Contributor(s) Vazquez F, Puigserver P
Citation(s) 23416000
Submission date Mar 28, 2012
Last update date Dec 06, 2018
Contact name Pere Puigserver
Phone 617-582-7977
Organization name Dana-Farber Cancer Institute
Street address 450 Brookline Av. CLSB-11144
City Boston
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (8)
GSM904724 shGFP-rep-1
GSM904725 shGFP-rep-2
GSM904726 shRNA-control-rep-1
BioProject PRJNA157003

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36879_RAW.tar 17.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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