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| Status |
Public on Apr 04, 2006 |
| Title |
The AIN-centered DCN of delayed-type eyeblink conditioned mice: 7-d paired and 7-d unpaired training groups |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Anterior interpositus nucleus (AIN) is a proposed site of memory formation of eyeblink conditioning. A large part of the underlying molecular events, however, remains unknown. To elucidate molecular mechanisms, we examined transcriptional changes in the AIN of mice trained with delayed-type eyeblink conditioning
Keywords: 7-d paired training, 7-d unpaired training, delayed-type eyeblink conditioning of mice, anterior interpositus nucleus-centered deep cerebellar nuclei
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| Overall design |
7-d paired training group: Mice received a surgery for implanting four Teflon-coated stainless-steel wires in their left eyelid and a headstage on their head. After 3days’ recovery, they were trained with paired paradigm of conditioned stimulus (CS) and unconditioned stimulus (US) for 7 days: A 352-ms tone CS (1kHz, 83~85dB) was delivered first and a 100ms periorbital shock US (100kHz square pluses) were delivered with 252ms after the onset of CS, and they co-terminated. In case of 7-d unpaired training group, A CS and a US were delivered in an explicitly unpaired, pseudorandomized manner for 7 days. After the last trial was given, anterior interpositus was immediately sampled in 10 to 30 min from the sacrifice.
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| Contributor(s) |
Park J, Nishimura S, Itohara S |
| Citation(s) |
16569693 |
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| Submission date |
Nov 23, 2005 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Jin-Sung Park |
| E-mail(s) |
parkjs@brain.riken.jp
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| Phone |
+81-48-462-9724
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| Organization name |
RIKEN
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| Department |
BSI
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| Lab |
Lab. for Behavioral Genetics
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| Street address |
2-1 Hirosawa
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| City |
Wako-shi |
| State/province |
Saitama |
| ZIP/Postal code |
351-0198 |
| Country |
Japan |
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| Platforms (3) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
| GPL82 |
[MG_U74Bv2] Affymetrix Murine Genome U74B Version 2 Array |
| GPL83 |
[MG_U74Cv2] Affymetrix Murine Genome U74 Version 2 Array |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE3713 |
The AIN-centered DCN of delayed-type eyeblink conditioned mice |
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| Relations |
| BioProject |
PRJNA94285 |
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