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Status |
Public on Apr 18, 2014 |
Title |
The effect of TGF-beta in Apc-mutated mouse intestinal organoids |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Intestinal crypts isolated from Apcflox/flox; villin-CreERT mice were treated with Tamoxifen to induce the deletion of Apc. Tamoxifen-treated organoids were selected in the absence of Wnt agonists and then treated with TGF-beta.
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Overall design |
Total RNA obtained from Tamoxifen-treated, Apc-deleted intestinal organoids in the absence or presence of 3 ng/ml TGF-beta (18h).
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Contributor(s) |
Wiener Z, Hyvonen V, Alitalo K |
Citation(s) |
24825889 |
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Submission date |
Jan 13, 2012 |
Last update date |
Jan 16, 2019 |
Contact name |
Zoltan Wiener |
E-mail(s) |
zoltan.wiener@helsinki.fi
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Organization name |
University of Helsinki
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Department |
Molecular Cancer Biology Programme
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Street address |
Haartmaninkatu 8
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City |
Helsinki |
ZIP/Postal code |
FI-00017 |
Country |
Finland |
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Platforms (1) |
GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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Samples (8)
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GSM861893 |
Apc-mutated organoid, tamoxifen, untreated 1 |
GSM861894 |
Apc-mutated organoid, tamoxifen, untreated 2 |
GSM861895 |
Apc-mutated organoid, tamoxifen, untreated 3 |
GSM861896 |
Apc-mutated organoid, tamoxifen, untreated 4 |
GSM861897 |
Apc-mutated organoid, tamoxifen, TGF-beta treated 1 |
GSM861898 |
Apc-mutated organoid, tamoxifen, TGF-beta treated 2 |
GSM861899 |
Apc-mutated organoid, tamoxifen, TGF-beta treated 3 |
GSM861900 |
Apc-mutated organoid, tamoxifen, TGF-beta treated 4 |
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This SubSeries is part of SuperSeries: |
GSE35094 |
Apc, Kras, and TGFbeta in intestinal organoids |
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Relations |
BioProject |
PRJNA156159 |