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| Status |
Public on Nov 21, 2011 |
| Title |
Methylation data from normal thymocytes, 24 day pre-tumor Dnmt3b-deficient thymocytes, Wild-Type Tumors, and Dnmt3b-deficient Tumors |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
Dnmt3b is a DNA methytransferase which is an enzyme that methylated genomic DNA which contributes to genomic stability and transcriptional regulation.
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| Overall design |
We genetically inactivated Dnmt3b in the hematopoeitic compartment in the context of MYC overexpression and analysed the resulting thymic lymphomas.
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| Contributor(s) |
Opavsky R, Hlady R, Opavska J, Novakova S, Klinkebiel D |
| Citation(s) |
22133874 |
| Submission date |
Nov 21, 2011 |
| Last update date |
Jul 20, 2018 |
| Contact name |
Ryan Hlady |
| E-mail(s) |
rhlady@unmc.edu
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| Phone |
4025595544
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| Organization name |
UNMC
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| Department |
Eppley
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| Lab |
Rene Opavsky
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| Street address |
985950 DRC II 4020
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| City |
Omaha |
| State/province |
Nebraska |
| ZIP/Postal code |
68198 |
| Country |
USA |
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| Platforms (1) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
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| Samples (16)
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| GSM837969 |
Normal Thymocytes, biological replicate 1 |
| GSM837970 |
Normal Thymocytes, biological replicate 2 |
| GSM837971 |
Normal Thymocytes, biological replicate 3 |
| GSM837972 |
Wild-Type Lymphoma, biological replicate 1 |
| GSM837973 |
Wild-Type Lymphoma, biological replicate 2 |
| GSM837974 |
Wild-Type Lymphoma, biological replicate 3 |
| GSM837975 |
Wild-Type Lymphoma, biological replicate 4 |
| GSM837976 |
Wild-Type Lymphoma, biological replicate 5 |
| GSM837977 |
Dnmt3b-deficient Lymphoma, biological replicate 1 |
| GSM837978 |
Dnmt3b-deficient Lymphoma, biological replicate 2 |
| GSM837979 |
Dnmt3b-deficient Lymphoma, biological replicate 3 |
| GSM837980 |
Dnmt3b-deficient Lymphoma, biological replicate 4 |
| GSM837981 |
Dnmt3b-deficient Lymphoma, biological replicate 5 |
| GSM837982 |
24 day pre-tumor Dnmt3b-deficient thymocytes, biological replicate 1 |
| GSM837983 |
24 day pre-tumor Dnmt3b-deficient thymocytes, biological replicate 2 |
| GSM837984 |
24 day pre-tumor Dnmt3b-deficient thymocytes, biological replicate 3 |
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| Relations |
| BioProject |
PRJNA148177 |
| Supplementary data files not provided |
| Raw data not provided for this record |
| Processed data included within Sample table |
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