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Status |
Public on Nov 10, 2011 |
Title |
Histone Deacetylase 3 is an Epigenomic Brake in Macrophage Alternative Activation (ChIP-Seq) |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We report the genomic regions enriched in Histone Deacetylase 3 (HDAC3) in mouse bone marrow derived macrophages. Furthermore, we also report the genomic acetylation pattern on Histone 3, Lysine 9 (H3K9) in macrophages with and without HDAC3 and/or treated with Th2 cytokine IL-4.
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Overall design |
HDAC3 enriched genomic regions in mouse bone marrow dervied macrophages and H3K9Ac enriched genomic regions in wild-type macrophages and macrophages treated with IL-4 and/or deficient in HDAC3.
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Contributor(s) |
Mullican SE, Gaddis CA, Alenghat T, Nair MG, Giacomin PR, Everett LJ, Feng D, Steger DJ, Schug J, Artis D, Lazar MA |
Citation(s) |
22156208, 24074869 |
Submission date |
Nov 09, 2011 |
Last update date |
May 15, 2019 |
Contact name |
Logan J Everett |
Organization name |
U.S. Environmental Protection Agency
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Department |
Office of Research and Development
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Lab |
Center for Computational Toxicology and Exposure
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Street address |
109 T.W. Alexander Dr
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City |
RTP |
State/province |
North Carolina |
ZIP/Postal code |
27711 |
Country |
USA |
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Platforms (1) |
GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
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Samples (7)
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This SubSeries is part of SuperSeries: |
GSE33609 |
Histone Deacetylase 3 is an Epigenomic Brake in Macropahge Alternative Activation |
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Relations |
SRA |
SRP009249 |
BioProject |
PRJNA154331 |