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| Status |
Public on Oct 31, 2011 |
| Title |
Expression data from paired matched breast cancer Fine needle aspiration (FNA) or Core needle biopsies (CBX) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Paired FNA and CBX specimens were prospectively collected from 37 breast cancers before any systemic therapy during a biomarker discovery study at The University of Texas M. D. Anderson Cancer Center.
We identified 293 probe sets overexpressed in core biopsies; these included five highly coexpressed gene clusters (metagenes) corresponding to immune functions and extracellular matrix components.
We compared gene expression profiles of pairs of fine-needle (stroma-poor) and core-needle (stroma-rich) biopsies from 37 cancers to identify stroma-associated genes
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| Overall design |
Pre-treatment paird matched FNA and CBX from primary tumors were obtained and RNA extracted and hybridized to afymetrix microarrays according to manufacturer protocol.
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| Contributor(s) |
Pusztai L, Bianchini G, Qi Y, Iwamoto T |
| Citation(s) |
22235097, 20805453 |
| |
| Submission date |
Sep 30, 2011 |
| Last update date |
Aug 10, 2018 |
| Contact name |
TAKAYUKI IWAMOTO |
| E-mail(s) |
tiwamoto@mdanderson.org
|
| Organization name |
UT MD Anderson
|
| Department |
Breast medical Oncology
|
| Street address |
1515 Holcombe Blvd
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030-4009 |
| Country |
USA |
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| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
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| Samples (74)
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| Relations |
| BioProject |
PRJNA147841 |
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