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| Status |
Public on Jan 31, 2012 |
| Title |
cis-Expression QTL Analysis of Established Risk Variants for Colorectal Cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions on the expression of neighboring genes.
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| Overall design |
Forty microsatellite stable and CpG island methylator phenotype-negative colorectal tumors and paired adjacent-normal colon tissues were used for genome-wide SNP and gene expression profiling in our cis-eQTL analyses.
This submission represents transcriptome component of study.
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| Contributor(s) |
Loo LW, Cheng I, Tiirikainen M, Lum-Jones A, Seifried A, Dunklee LM, Church JM, Gryfe R, Weisenberger DJ, Haile RW, Gallinger S, Duggan DJ, Thibodeau SN, Casey G, Marchand LL |
| Citation(s) |
22363440, 23341073 |
| |
| Submission date |
Aug 30, 2011 |
| Last update date |
Feb 03, 2020 |
| Contact name |
Lenora WM Loo |
| E-mail(s) |
lloo@cc.hawaii.edu
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| Organization name |
University of Hawaii Cancer Center
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| Department |
Epidemiology Program
|
| Street address |
1236 Lauhala St #407
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| City |
Honolulu |
| State/province |
HI |
| ZIP/Postal code |
96813 |
| Country |
USA |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (80)
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| GSM787768 |
Colon Tissue, Tumor, 444667 |
| GSM787769 |
Colon Tissue, Normal, 462 |
| GSM787770 |
Colon Tissue, Tumor, 462 |
| GSM787771 |
Colon Tissue, Normal, 475 |
| GSM787772 |
Colon Tissue, Tumor, 475 |
| GSM787773 |
Colon Tissue, Normal, 499696 |
| GSM787774 |
Colon Tissue, Tumor, 499696 |
| GSM787775 |
Colon Tissue, Normal, 552 |
| GSM787776 |
Colon Tissue, Tumor, 552 |
| GSM787777 |
Colon Tissue, Normal, 615 |
| GSM787778 |
Colon Tissue, Tumor, 615 |
| GSM787779 |
Colon Tissue, Normal, 616 |
| GSM787780 |
Colon Tissue, Tumor, 616 |
| GSM787781 |
Colon Tissue, Normal, 687 |
| GSM787782 |
Colon Tissue, Tumor, 687 |
| GSM787783 |
Colon Tissue, Normal, 723 |
| GSM787784 |
Colon Tissue, Tumor, 723 |
| GSM787785 |
Colon Tissue, Tumor, 736 |
| GSM787786 |
Colon Tissue, Normal, 736 |
| GSM787787 |
Colon Tissue, Normal, 746 |
| GSM787788 |
Colon Tissue, Tumor, 746 |
| GSM787789 |
Colon Tissue, Normal, 756 |
| GSM787790 |
Colon Tissue, Tumor, 756 |
| GSM787791 |
Colon Tissue, Normal, 762 |
| GSM787792 |
Colon Tissue, Tumor, 762 |
| GSM787793 |
Colon Tissue, Normal, 788 |
| GSM787794 |
Colon Tissue, Tumor, 788 |
| GSM787795 |
Colon Tissue, Normal, 809 |
| GSM787796 |
Colon Tissue, Tumor, 809 |
| GSM787797 |
Colon Tissue, Normal, 832 |
| GSM787798 |
Colon Tissue, Tumor, 832 |
| GSM787799 |
Colon Tissue, Tumor, RT-116 |
| GSM787800 |
Colon Tissue, Normal, RT-116 |
| GSM787801 |
Colon Tissue, Normal, RT-122 |
| GSM787802 |
Colon Tissue, Tumor, RT-122 |
| GSM787803 |
Colon Tissue, Normal, RT-158 |
| GSM787804 |
Colon Tissue, Tumor, RT-158 |
| GSM787805 |
Colon Tissue, Normal, RT-203 |
| GSM787806 |
Colon Tissue, Tumor, RT-203 |
| GSM787807 |
Colon Tissue, Normal, RT-272 |
| GSM787808 |
Colon Tissue, Tumor, RT-272 |
| GSM787809 |
Colon Tissue, Tumor, RT-294 |
| GSM787810 |
Colon Tissue, Normal, RT-294 |
| GSM787811 |
Colon Tissue, Normal, RT-312 |
| GSM787812 |
Colon Tissue, Tumor, RT-312 |
| GSM787813 |
Colon Tissue, Normal, RT-329 |
| GSM787814 |
Colon Tissue, Tumor, RT-329 |
| GSM787815 |
Colon Tissue, Normal, RT-340 |
| GSM787816 |
Colon Tissue, Tumor, RT-340 |
| GSM787817 |
Colon Tissue, Tumor, RT-358 |
| GSM787818 |
Colon Tissue, Normal, RT-358 |
| GSM787819 |
Colon Tissue, Normal, RT-380 |
| GSM787820 |
Colon Tissue, Tumor, RT-380 |
| GSM787821 |
Colon Tissue, Tumor, RT-432 |
| GSM787822 |
Colon Tissue, Normal, RT-432 |
| GSM787823 |
Colon Tissue, Normal, RT-434 |
| GSM787824 |
Colon Tissue, Tumor, RT-434 |
| GSM787825 |
Colon Tissue, Normal, RT-455 |
| GSM787826 |
Colon Tissue, Tumor, RT-455 |
| GSM787827 |
Colon Tissue, Tumor, RT-465 |
| GSM787828 |
Colon Tissue, Normal, RT-465 |
| GSM787829 |
Colon Tissue, Normal, RT-483 |
| GSM787830 |
Colon Tissue, Tumor, RT-483 |
| GSM787831 |
Colon Tissue, Normal, RT-567 |
| GSM787832 |
Colon Tissue, Tumor, RT-567 |
| GSM787833 |
Colon Tissue, Normal, RT-58 |
| GSM787834 |
Colon Tissue, Tumor, RT-58 |
| GSM787835 |
Colon Tissue, Normal, RT-606 |
| GSM787836 |
Colon Tissue, Tumor, RT-606 |
| GSM787837 |
Colon Tissue, Normal, RT-608 |
| GSM787838 |
Colon Tissue, Tumor, RT-608 |
| GSM787839 |
Colon Tissue, Normal, RT-677 |
| GSM787840 |
Colon Tissue, Tumor, RT-677 |
| GSM787841 |
Colon Tissue, Normal, RT-721 |
| GSM787842 |
Colon Tissue, Tumor, RT-721 |
| GSM787843 |
Colon Tissue, Normal, RT-87 |
| GSM787844 |
Colon Tissue, Tumor, RT-87 |
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| Relations |
| BioProject |
PRJNA145435 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE31737_RAW.tar |
1.7 Gb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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