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Series GSE30432 Query DataSets for GSE30432
Status Public on Sep 03, 2013
Title Gene expression profiling of ElonginA knocked-down Hela cells in the presence of Doxorubicin
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptional elongation factor Elongin A exhibits an activity to repress the temporary pause of RNA polymerase II (RNAPII) on the DNA template, resulting in increase of mRNA synthesis in vitro. However, actual elongation ability of Elongin A in mammalian cells has not been determined yet. To elucidate the practical transcriptional role of mammalian Elongin A in vivo, we carried out whole genome expression analysis using Elongin A knocked-down HeLa cells.
Overall design Gene expression in Elongin A knocked-down HeLa cells was measured at 2 hours after doxorubicin treatment (1microM).
Contributor(s) Kawauchi J, Kitajima S
Citation(s) 23828199
Submission date Jul 06, 2011
Last update date Feb 22, 2018
Contact name Junya Kawauchi
Organization name Tokyo Medical & Dental University
Department Medical Research Institute
Lab Biochemical Genetics
Street address Yushima 1-5-45
City Bunkyo-ku
State/province Tokyo
ZIP/Postal code 113-8510
Country Japan
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (2)
GSM754838 siControl HeLa DOX
GSM754839 siEloA HeLa DOX
BioProject PRJNA143535

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Supplementary file Size Download File type/resource
GSE30432_RAW.tar 21.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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