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| Status |
Public on Aug 14, 2011 |
| Title |
Expression data of ribosomal proteins from sorted hematopoietic stems cells from patients with low risk MDS. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
A role for reduced ribosomal protein gene dosage in both DBA and 5q- MDS suggests that other forms of MDS might also involve altered expression of ribosomal protein genes.
We used microarrays to interrogate the expression of ribosomal proteins from purified hematopoietic stems cells from patients with low risk myelodysplastic syndrome and age-matched healthy controls.
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| Overall design |
Hematopoietic stem cells were sorted from 8 patients with low risk myelodysplastic syndrome and 11 age-matched healthy controls, and total RNA was hybridized to Affymetrix microarrays.
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| Contributor(s) |
McGowan KA, Park CY, Park GS |
| Citation(s) |
21788341 |
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| Submission date |
Jun 24, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Christopher Park |
| E-mail(s) |
parkc@mskcc.org
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| Organization name |
MSKCC
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| Street address |
1275 York Avenue
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (19)
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| GSM747513 |
HSC patient 1, RCMD, IPSS low risk |
| GSM747514 |
HSC patient 2, RCMD-RS, IPSS low risk |
| GSM747515 |
HSC patient 3, RCMD, IPSS INT-1 risk |
| GSM747516 |
HSC patient 4, RCMD, IPSS low risk |
| GSM747517 |
HSC patient 5, RARS, IPSS low risk |
| GSM747518 |
HSC patient 6, RCMD-RS, IPSS low risk |
| GSM747519 |
HSC patient 7, RCMD-RS, IPSS low risk |
| GSM747520 |
HSC patient 8, RCMD, IPSS low risk |
| GSM747521 |
HSC normal 1 |
| GSM747522 |
HSC normal 2 |
| GSM747523 |
HSC normal 3 |
| GSM747524 |
HSC normal 4 |
| GSM747525 |
HSC normal 5 |
| GSM747526 |
HSC normal 6 |
| GSM747527 |
HSC normal 7 |
| GSM747528 |
HSC normal 8 |
| GSM747529 |
HSC normal 9 |
| GSM747530 |
HSC normal 10 |
| GSM747531 |
HSC normal 11 |
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| Relations |
| BioProject |
PRJNA143957 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE30201_RAW.tar |
81.5 Mb |
(http)(custom) |
TAR (of CEL) |
| GSE30201_ribosomal_gene_matrix.txt.gz |
33.0 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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