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| Status |
Public on May 22, 2006 |
| Title |
The gene expression program of the developing mammary gland |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The developing mammary gland contains distinct microenvironments that perform specialized functions for branching and ductal invasion. These microenvironments include the terminal end buds (TEBs) at the tips of invading primary ducts and the more differentiated proximal ducts that give rise to side branches. We have devised a novel microarray approach to identify genes that are expressed in the epithelium and stroma of these distinct microenvironments.
Keywords: spotted oligonucleotide
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| Overall design |
Total RNA from microdissected terminal end buds and mature ducts were compared to epithelium-free distal stroma of 5 week old mammary glands. B-actin-GFP reporter mice were used to visualize the mammary glands for microdissection.
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| Contributor(s) |
Kouros-Mehr H, Werb Z |
| Citation(s) |
16079154, 17129787, 17039550 |
| |
| Submission date |
Jul 22, 2005 |
| Last update date |
Jan 29, 2013 |
| Contact name |
Hosein Kouros-Mehr |
| E-mail(s) |
kouros.mehr@gmail.com
|
| Phone |
317-217-9487
|
| Organization name |
Eli Lilly
|
| Department |
Oncology
|
| Street address |
533 Merrill St.
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46204 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL2660 |
UCSF 12Mm Mouse v.2 Oligo Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA91939 |
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