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| Status |
Public on Jan 01, 2014 |
| Title |
Impact of Visceral Fat on Gene Expression Profile in Peripheral Blood Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We profiled gene expression in peripheral blood cells from 28 obese patients by microarray analysis and visceral fat accumulation caused the gene expression proliles especially in circadian rhythm, inflammation, oxidative stress, and immune response.
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| Overall design |
Obesity was defined as body mass index (BMI) greater than 25 kg/m2 according to the Japanese criteria and visceral fat area (VFA) was estimated by abdominal bioelectrical impedance analysis. Subjects with type 1 diabetes mellitus, autoimmune diseases, malignant diseases, and infectious diseases were excluded. Patients treated with statin and/or thiazolidinediones were also excluded.
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| Contributor(s) |
Yamaoka M, Maeda N, Nakamura S, Matsubara K, Funahashi T, Shimomura I |
| Citation(s) |
23091619, 24516558 |
| |
| Submission date |
Mar 18, 2011 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Norikazu Maeda |
| Organization name |
Osaka University
|
| Department |
Graduate School of Medicine
|
| Lab |
Metabolic Medicine
|
| Street address |
2-2-B5
|
| City |
Suita |
| State/province |
Osaka |
| ZIP/Postal code |
565-0871 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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| Samples (28)
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| Relations |
| BioProject |
PRJNA137947 |
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