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Series GSE27536 Query DataSets for GSE27536
Status Public on Nov 16, 2013
Title Vastus lateralis biopsies from healthy and COPD patients before and after 8 weeks of exercise training
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Study the training exercise effects in chronic obstructive pulmonary disease (COPD) patients and aged-matched healthy individuals. Skeletal muscle biopsies from 9 stable COPD patients with normal fat free mass index (FFMI, 21Kg/m2) (COPDN), 6 COPD patients with low FFMI (16Kg/m2) (COPL), and 12 healthy sedentary subjects (FFMI 21Kg/m2) before and after 8 weeks of a supervised endurance exercise program were analyzed.
 
Overall design Samples were collected from open biopsies from the musculus vastus lateralis of COPD patients and healthy individuals before and after 8 weeks of exercise training. Constant-work rate exercise at 70% of pre-training Watts peak (Wpeak) (CardiO2 cycle Medical Graphics Corporation, USA) was carried out before and after 8 weeks of supervised interval training with a cycloergometer until pre-training endurance time exhaustion. Measurements before and after training were obtained at isowork-rate and iso-time.
 
Contributor(s) Kalko S, Falciani F, Roca J
Citation(s) 21909251
Submission date Feb 25, 2011
Last update date Mar 25, 2019
Contact name Nil Turan
E-mail(s) philipp.antczak@gmail.com
Organization name University of Birmingham
Street address University of Birmingham, Edgbaston
City Birmingham
ZIP/Postal code B15 2TT
Country United Kingdom
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (54)
GSM680029 Muscle biopsies from healthy sedentary individual #1
GSM680030 Muscle biopsies from healthy sedentary individual #10
GSM680031 Muscle biopsies from healthy sedentary individuals #11
Relations
BioProject PRJNA138553

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE27536_RAW.tar 421.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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