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| Status |
Public on Aug 31, 2024 |
| Title |
Single-cell RNA sequencing of murine kidneys for ischemia-reperfusion induced renal injury and fibrosis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Using single-cell RNA sequencing (scRNA-seq), we isolated approximately 100,000 cells from mouse kidneys and generated a large-scale transcriptomic dataset corresponding to time points of 4 hours, 12 hours, 1 day, 5 days, 14 days, and 28 days after IR. Our preliminary analysis identified 16 distinct cell types, providing a robust database to study the changes and evolution of renal IRI from early to late stages.
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| Overall design |
C57BL/6 mice were euthanized at 4 hours, 12 hours, 1 day, 5 days, 14 days, and 28 days after IR, and analyzed using scRNA-seq.
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| Contributor(s) |
Zeng R, Yao Y, Xu G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 14, 2024 |
| Last update date |
Aug 31, 2024 |
| Contact name |
Yinzheng Li |
| Organization name |
Division of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
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| Street address |
No. 1095, Jiefang Avenue, Wuhan, China. 430030
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| City |
Wuhan |
| ZIP/Postal code |
430030 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA1148121 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE274819_RAW.tar |
888.3 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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