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| Status |
Public on Aug 20, 2024 |
| Title |
The mechanism of cardiotoxicity induced by evodiamine and matrine was revealed by epitranscriptomics |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
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| Summary |
By using epitranscriptomics, the mechanism of cardiotoxicity induced by evodiamine and matrine was discovered. Experimental findings indicated that evodiamine and matrine altered m6A levels within the cells.
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| Overall design |
To investigate whether m6A modification is involved in cardiotoxicity following evodiamine and matrine treatment, we performed MeRIP-seq on control cells and cells treated with evodiamine and matrine.
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| Contributor(s) |
Liao D, Fang G, Shen Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 13, 2024 |
| Last update date |
Aug 20, 2024 |
| Contact name |
Dongshan Liao |
| E-mail(s) |
lds89612@fjmu.edu.cn
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| Organization name |
福建医科大学附属协和医院
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| Street address |
福建省福州市鼓楼区新权路29号
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| City |
Fuzhou |
| ZIP/Postal code |
350001 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA1147763 |
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