|
| Status |
Public on Aug 31, 2024 |
| Title |
RNAseq analysis of mouse monocytes exposed to IL4 ex vivo |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Immune cells can rapidly adapt their functional program in response to cytokines. How cytokine-induced transcriptional responses are affected by micro-environmental cues remains poorly understood. The Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor sensing environmental signals including metabolites. Here we addressed the cross-talk between Interleukin-4 and AhR signaling in monocytes.
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| Overall design |
We analysed the transcriptome of mouse monocytes (wild-type or deficient for AhR) to IL-4 after 3h of ex vivo exposure.
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| Contributor(s) |
Segura E |
| Citation missing |
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| |
| Submission date |
May 29, 2024 |
| Last update date |
Aug 31, 2024 |
| Contact name |
Elodie Segura |
| E-mail(s) |
elodie.segura@curie.fr
|
| Phone |
+336156246720
|
| Organization name |
Institut Curie
|
| Department |
INSERM U932
|
| Street address |
26 rue d'Ulm
|
| City |
Paris |
| ZIP/Postal code |
75005 |
| Country |
France |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA1117938 |
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