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| Status |
Public on Jul 01, 2024 |
| Title |
Microglial heterogeneity in the ischemic stroke mouse brain of both sexes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The objective of the current study was to dissect the effect of permanent stroke on the diversity of microglia, the resident immune cells within the brain parenchyma.
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| Overall design |
To characterize microglial diversity after permanent stroke in Tmem119-2A-CreERT2;Ai6 mice in which microglia were labeled with ZsGreen, we sorted ZsGreen positive cells on day 3 after stroke for scRNA-seq analysis. Four samples were analayzed: female_sham, female_stroke, male_sham, and male_stroke, (F_Sham, F_Stroke, M_Sham, M_Stroke). Each sample were pooled from 4 mice.
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| Contributor(s) |
del Aguila A, Jain V, Yang W |
| Citation(s) |
39095897 |
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| Submission date |
May 11, 2024 |
| Last update date |
Aug 23, 2024 |
| Contact name |
Wei Yang |
| E-mail(s) |
yang.lab.duke@gmail.com
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| Organization name |
Duke University
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| Street address |
300 Duke Street
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| City |
Durham |
| State/province |
United States |
| ZIP/Postal code |
27701 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA1110600 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE267240_RAW.tar |
191.6 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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