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| Status |
Public on Jun 30, 2024 |
| Title |
Macrophage-mediated myelin recycling fuels brain cancer malignancy |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://doi.org/10.1016/j.cell.2024.07.030
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| |
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| Citation(s) |
39137777 |
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| Submission date |
Apr 29, 2024 |
| Last update date |
Sep 18, 2024 |
| Contact name |
Daan Juri Kloosterman |
| E-mail(s) |
d.kloosterman@nki.nl
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| Phone |
0640168513
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| Organization name |
The Netherlands Cancer
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| Department |
Tumor Biology & Immunology
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| Lab |
L. Akkari
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| Street address |
Plesmanlaan 121
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| City |
Amsterdam |
| ZIP/Postal code |
1066 CX |
| Country |
Netherlands |
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| Platforms (2) |
| GPL21626 |
NextSeq 550 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (110)
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| GSM8241358 |
Non-lipid-laden monocyte-derived macrophages, mn:547 |
| GSM8241359 |
Lipid-laden monocyte-derived macrophages, mn:547 |
| GSM8241360 |
Non-lipid-laden microglia, mn:547 |
| GSM8241361 |
Lipid-laden microglia, mn:547 |
| GSM8241362 |
Non-lipid-laden monocyte-derived macrophages, mn:546 |
| GSM8241363 |
Lipid-laden monocyte-derived macrophages, mn:546 |
| GSM8241364 |
Non-lipid-laden microglia, mn:546 |
| GSM8241365 |
Lipid-laden microglia, mn:546 |
| GSM8241366 |
Non-lipid-laden monocyte-derived macrophages, mn:545 |
| GSM8241367 |
Lipid-laden monocyte-derived macrophages, mn:545 |
| GSM8241368 |
Non-lipid-laden microglia, mn:545 |
| GSM8241369 |
Lipid-laden microglia, mn:545 |
| GSM8241370 |
BMDMs Control, mn:957 |
| GSM8241371 |
BMDMs Full Tumor, mn:957 |
| GSM8241372 |
BMDMs Tumor without Myelin, mn:957 |
| GSM8241373 |
BMDMs Myelin Alone, mn:957 |
| GSM8241374 |
BMDMs Control, mn:958 |
| GSM8241375 |
BMDMs Full Tumor, mn:958 |
| GSM8241376 |
BMDMs Tumor without Myelin, mn:958 |
| GSM8241377 |
BMDMs Myelin Alone, mn:958 |
| GSM8241378 |
BMDMs Control, mn:016 |
| GSM8241379 |
BMDMs Full Tumor, mn:016 |
| GSM8241380 |
BMDMs Tumor without Myelin, mn:016 |
| GSM8241381 |
BMDMs Myelin Alone, mn:016 |
| GSM8241406 |
Mono-culture, Macrophage, 0 hours post myelin, mn:001 |
| GSM8241407 |
Mono-culture, Tumor cell, 0 hours post myelin, mn:001 |
| GSM8241408 |
Co-culture, Macrophage, 0 hours post myelin, mn:001 |
| GSM8241409 |
Co-culture, Tumor cell, 0 hours post myelin, mn:001 |
| GSM8241410 |
Mono-culture, Macrophage, 6 hours post myelin, mn:001 |
| GSM8241411 |
Mono-culture, Tumor cell, 6 hours post myelin, mn:001 |
| GSM8241412 |
Co-culture, Macrophage, 6 hours post myelin, mn:001 |
| GSM8241413 |
Co-culture, Tumor cell, 6 hours post myelin, mn:001 |
| GSM8241414 |
Mono-culture, Macrophage, 24 hours post myelin, mn:001 |
| GSM8241415 |
Mono-culture, Tumor cell, 24 hours post myelin, mn:001 |
| GSM8241416 |
Co-culture, Macrophage, 24 hours post myelin, mn:001 |
| GSM8241417 |
Co-culture, Tumor cell, 24 hours post myelin, mn:001 |
| GSM8241418 |
Mono-culture, Macrophage, 0 hours post myelin, mn:002 |
| GSM8241419 |
Mono-culture, Tumor cell, 0 hours post myelin, mn:002 |
| GSM8241420 |
Co-culture, Macrophage, 0 hours post myelin, mn:002 |
| GSM8241421 |
Co-culture, Tumor cell, 0 hours post myelin, mn:002 |
| GSM8241422 |
Mono-culture, Macrophage, 6 hours post myelin, mn:002 |
| GSM8241423 |
Mono-culture, Tumor cell, 6 hours post myelin, mn:002 |
| GSM8241424 |
Co-culture, Macrophage, 6 hours post myelin, mn:002 |
| GSM8241425 |
Co-culture, Tumor cell, 6 hours post myelin, mn:002 |
| GSM8241426 |
Mono-culture, Macrophage, 24 hours post myelin, mn:002 |
| GSM8241427 |
Mono-culture, Tumor cell, 24 hours post myelin, mn:002 |
| GSM8241428 |
Co-culture, Macrophage, 24 hours post myelin, mn:002 |
| GSM8241429 |
Co-culture, Tumor cell, 24 hours post myelin, mn:002 |
| GSM8241430 |
Mono-culture, Macrophage, 0 hours post myelin, mn:003 |
| GSM8241431 |
Mono-culture, Tumor cell, 0 hours post myelin, mn:003 |
| GSM8241432 |
Co-culture, Macrophage, 0 hours post myelin, mn:003 |
| GSM8241433 |
Co-culture, Tumor cell, 0 hours post myelin, mn:003 |
| GSM8241434 |
Mono-culture, Macrophage, 6 hours post myelin, mn:003 |
| GSM8241435 |
Mono-culture, Tumor cell, 6 hours post myelin, mn:003 |
| GSM8241436 |
Co-culture, Macrophage, 6 hours post myelin, mn:003 |
| GSM8241437 |
Co-culture, Tumor cell, 6 hours post myelin, mn:003 |
| GSM8241438 |
Mono-culture, Macrophage, 24 hours post myelin, mn:003 |
| GSM8241439 |
Mono-culture, Tumor cell, 24 hours post myelin, mn:003 |
| GSM8241440 |
Co-culture, Macrophage, 24 hours post myelin, mn:003 |
| GSM8241441 |
Co-culture, Tumor cell, 24 hours post myelin, mn:003 |
| GSM8241442 |
Non-lipid-laden microglia, mn:224 |
| GSM8241443 |
Lipid-laden microglia, mn:224 |
| GSM8241444 |
Non-lipid-laden monocyte-derived macrophages, mn:224 |
| GSM8241445 |
Lipid-laden monocyte-derived macrophages, mn:224 |
| GSM8241446 |
Non-lipid-laden microglia, mn:221 |
| GSM8241447 |
Lipid-laden microglia, mn:221 |
| GSM8241448 |
Non-lipid-laden monocyte-derived macrophages, mn:221 |
| GSM8241449 |
Lipid-laden monocyte-derived macrophages, mn:221 |
| GSM8241450 |
Non-lipid-laden microglia, mn:431 |
| GSM8241451 |
Lipid-laden microglia, mn:431 |
| GSM8241452 |
Non-lipid-laden monocyte-derived macrophages, mn:431 |
| GSM8241453 |
Non-lipid-laden microglia, mn:718 |
| GSM8241454 |
Lipid-laden microglia, mn:718 |
| GSM8241455 |
Non-lipid-laden monocyte-derived macrophages, mn:718 |
| GSM8241456 |
Lipid-laden monocyte-derived macrophages, mn:718 |
| GSM8241457 |
MG, Primary PDG-p53 |
| GSM8241458 |
MDMs, Primary PDG-p53 |
| GSM8241459 |
MG, Recurrent PDG-p53 |
| GSM8241460 |
MDMs, Recurrent PDG-p53 |
| GSM8241461 |
MDMs, Primary PDG-Ink4a |
| GSM8241462 |
MG, Primary PDG-Ink4a |
| GSM8241463 |
MDMs, Recurrent PDG-Ink4a |
| GSM8241464 |
MG, Recurrent PDG-Ink4a |
| GSM8241465 |
MG, Non-tumor bearing |
| GSM8241466 |
CD45-/CD45+, PDG-Ink4a Primary, b |
| GSM8241467 |
CD45-/CD45+, PDG-p53 Primary, a |
| GSM8241468 |
CD45-/CD45+, PDG-Ink4a Primary, c |
| GSM8241469 |
CD45-/CD45+, PDG-p53 Recurrent, a |
| GSM8241470 |
CD45-/CD45+, PDG-Ink4a Recurrent, b |
| GSM8241471 |
CD45-/CD45+, PDG-Ink4a Recurrent, c |
| GSM8241472 |
CD45-/CD45+, PDG-p53 Primary, b |
| GSM8241473 |
CD45-/CD45+, PDG-p53 Primary, c |
| GSM8241474 |
CD45-/CD45+, PDG-p53 Primary, d |
| GSM8241475 |
CD45-/CD45+, PDG-Ink4a Primary, d |
| GSM8241476 |
CD45-/CD45+, PDG-Ink4a Recurrent, d |
| GSM8241477 |
CD45-/CD45+, PDG-p53 Recurrent, b |
| GSM8241478 |
CD45-/CD45+, PDG-p53 Recurrent, c |
| GSM8241481 |
PDG-Inka Primary, replicate 1 |
| GSM8241482 |
PDG-Inka Recurrent, replicate 1 |
| GSM8241483 |
PDG-Inka Primary, replicate 2 |
| GSM8241484 |
PDG-Inka Recurrent, replicate 2 |
| GSM8241485 |
PDG-Inka Recurrent, replicate 3 |
| GSM8241486 |
PDG-p53 Primary, replicate 1 |
| GSM8241487 |
PDG-Ink4a Primary, replicate 3 |
| GSM8241488 |
PDG-p53 Primary, replicate 2 |
| GSM8241489 |
PDG-p53 Primary, replicate 3 |
| GSM8241490 |
PDG-p53 Recurrent, replicate 1 |
| GSM8241491 |
PDG-p53 Recurrent, replicate 2 |
| GSM8241492 |
PDG-p53 Recurrent, replicate 3 |
| GSM8241493 |
PDG-Ink4a Primary, replicate 4 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE266140 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (ATAC-Seq) |
| GSE266141 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (RNA-Seq ex vivo) |
| GSE266143 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (RNA-Seq in vitro) |
| GSE266144 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (RNA-Seq in vivo) |
| GSE266145 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (scRNA-Seq) |
| GSE266147 |
Macrophage-mediated myelin recycling fuels brain cancer malignancy (VISIUM) |
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| Relations |
| BioProject |
PRJNA1105987 |
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