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| Status |
Public on Jun 04, 2024 |
| Title |
RNA-seq analysis of intestinal epithelia of Ruminococcus torques treated mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Purpose: To explore the influence of Ruminococcus torques treatment in mice intestinal epithelia. Method: Mice were pretreated with antibiotics for 3 days, then mice were fed with a high-fat diet and gavaged with PBS or R. torques (108 CFU/mouse) every 3 days for 2 weeks. mRNA profiles were generated by deep sequencing.Results: Several signaling pathways were changed after R. torques treatment, including response to hypoxia pathway. R. torques treatment significantly inhibits Epas1-mediated transcription effect.
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| Overall design |
Expression profiling by RNA-seq, profiling of intestinal epithelia after R. torques treatment.
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| Contributor(s) |
Zhang Y, Wang X, Jiang C, Pang Y |
| Citation(s) |
39079531 |
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| Submission date |
Apr 25, 2024 |
| Last update date |
Sep 03, 2024 |
| Contact name |
Chuan Ye |
| Organization name |
Peking University
|
| Street address |
38 Xueyuan Road, Haidian District
|
| City |
Beijing |
| ZIP/Postal code |
100191 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1104543 |
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