|
| Status |
Public on Dec 15, 2011 |
| Title |
Expression Profiling of Pancreatic Xenografts and Cell Lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Expression profiling of 70 Pancreatic Ductal Adenocarcinoma (PDAC) samples was performed on Agilent 44K expression arrays for cancer gene discovery. Additionally, matched aCGH on Agilent 244K arrays was performed. These two datasets were integrated in order to identify driver mutations leading to pancreatic cancer. Promising candidates were interrogated further using functional studies.
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| |
|
| Overall design |
68 tumor samples (48 xenografts, 20 cell lines). 2 color arrays hybridized against a common reference pool of RNA from 11 cancer cell lines
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| |
|
| Contributor(s) |
Shain AH |
| Citation(s) |
22233809 |
| |
| Submission date |
Dec 15, 2010 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Alan Hunter Shain |
| E-mail(s) |
hshain@gmail.com
|
| Organization name |
University of California San Francisco
|
| Department |
Pathology and Dermatology
|
| Lab |
Boris Bastian
|
| Street address |
555 MISSION BAY SOUTH BLVD RM 282 # 3118
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158-2156 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
|
| Samples (68)
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| This SubSeries is part of SuperSeries: |
| GSE26089 |
Expression Profiling and Array Comparative Genomic Hybridization of Pancreatic Xenografts and Cell Lines |
|
| Relations |
| BioProject |
PRJNA142407 |
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