|
| Status |
Public on Apr 18, 2024 |
| Title |
Body mass index alone may not serve as a reliable indicator of the risk of developing rheumatoid arthritis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Obesity is recognized as a risk factor for triggering rheumatoid arthritis (RA), and it can worsen joint deformities and diminish the quality of life in patients with RA. The reduction of body weight in obese individuals is believed to alleviate RA symptoms。
|
| |
|
| Overall design |
To further investigate whether obesity influences RA, we established collagen-induced-arthritis (CIA) models in mice using both regular and high-fat diets (HFD), and collected synovial tissue and performed RNA sequencing.
|
| Web link |
https://doi.org/10.1136/rmdopen-2023-003869
|
| |
|
| Contributor(s) |
Wang Y, Xie Q, Liang J, Yang K, Shen Y, Peng X, Tan H, Liu L |
| Citation(s) |
38580349 |
| |
| Submission date |
Feb 28, 2024 |
| Last update date |
Aug 22, 2024 |
| Contact name |
jianhui liang |
| E-mail(s) |
jh.liang@siat.ac.cn
|
| Organization name |
Shenzhen Institute of Science and Technology
|
| Street address |
1068 Xueyuan Avenue, Nanshan District
|
| City |
Shenzhen |
| State/province |
Guangdong |
| ZIP/Postal code |
518000 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (11)
|
|
| Relations |
| BioProject |
PRJNA1081810 |
Less...
More...