|
| Status |
Public on Feb 23, 2024 |
| Title |
Clinical and genomic characterization of chemoradiation resistant HPV-positive squamous cell carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This study performed genomic sequencing on a rare phenotype of HPV-positive oropharyngeal squamous cell carcinoma which was resistant to standard of care platinum based chemoradiation treatment. Tissue was collected from archival FFPE when available from pretreatment and post treamtent samples from four patients and these were batch corrected to be compared to known HPV-positive tumors without recurrent disease
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| |
|
| Overall design |
Tumor tissue from patients with chemoradiation resistant HPV positive oropharyngeal cancer tumors
Authors declare that raw files are planned to be submitted to dbGAP. In the interim, they are available upon request from corresponding author Theresa Guo (twguo@health.ucsd.edu)
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Submitter states that missing raw data are being made available for controlled access in dbGaP.
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| |
|
| Contributor(s) |
Guo T, Zamuner F, Gaykalova D, Mehra R |
| Citation(s) |
38505587 |
| |
| Submission date |
Feb 19, 2024 |
| Last update date |
Apr 04, 2024 |
| Contact name |
Theresa Guo |
| E-mail(s) |
twguo@health.ucsd.edu
|
| Organization name |
University of California, San Diego
|
| Street address |
3855 Health Sciences Dr, MC 0987
|
| City |
La Jolla |
| State/province |
California |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (83)
|
|
| Relations |
| BioProject |
PRJNA1077932 |
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