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Status |
Public on Mar 01, 2024 |
Title |
Polystyrene nano- and microplastic particles induce an inflammatory gene expression profile in neural stem cell-derived astrocytes |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Cellular uptake and cytotoxicity data from neural cells treated with microplastics were compared and contrasted. Transcriptomic data obtained by RNA-seq from astrocytes treated with microplastics was assessed further.
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Overall design |
Compare and contrast cellular uptake and cytotoxicity data for various neural cells and compare trascriptomics data between control- and microplastic-treated astrocytes using RNA-seq.
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Contributor(s) |
Marcellus KA, Bugiel S, Nunnikhoven A, Curran IH, Gill S |
Citation missing |
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Submission date |
Feb 19, 2024 |
Last update date |
Mar 01, 2024 |
Contact name |
Santokh Gill |
E-mail(s) |
santokh.gill@hc-sc.gc.ca
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Organization name |
Health Canada
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Department |
251 Sir Frederick Banting Driveway
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Street address |
251 SIR FREDERICK BANTING
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City |
Ottawa |
State/province |
Ontario |
ZIP/Postal code |
K1A 0K9 |
Country |
Canada |
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Platforms (1) |
GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
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Samples (32)
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Relations |
BioProject |
PRJNA1077930 |