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| Status |
Public on Sep 18, 2024 |
| Title |
Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy (kdSdc1 and mutant) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the function of SDC1 in the regulation of anti-tumor immunity, we established B16 and MC38 cell lines in which sdc1 or control RNA has been knocked down by shRNA.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for B16 and MC38 cell lines representing sdc1 knockdown, sdc1 knockdown+c30 mutant, sdc1 knockdown+ect mutant, sdc1 knockdown+sdc1 wt, that were stimulated with IFNr.
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| Contributor(s) |
Liu Y, Xu C, Li Z, Liu Y |
| Citation(s) |
39259785 |
| |
| Submission date |
Jan 30, 2024 |
| Last update date |
Sep 18, 2024 |
| Contact name |
Liu Yongzhong |
| E-mail(s) |
liuyzg@shsci.org
|
| Organization name |
Shanghai Cancer Institute
|
| Street address |
ShanghaiJiaoTongUniversity,MinhangDistrict,Shanghai,China,No.800DongchuanRoad
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| City |
Shanghai |
| ZIP/Postal code |
200000 |
| Country |
China |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA1071144 |
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