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Series GSE252176 Query DataSets for GSE252176
Status Public on May 17, 2024
Title Multi-Omics molecular subtyping based on commensal microbiome predicts molecular characteristics and therapeutic response in Triple-Negative Breast Cancer [Spatial Transcriptome seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We thoroughly analyzed the molecular subtyping of Triple-Negative Breast Cancer and its different manifestations, and located T cells and Tumor cells related to the survival of breast cancer through single cell sequencing and space transcriptome according to our score, and finally investigated their relationship with the therapeutic efficacy, providing a scientific basis for the treatment of triple negative breast cancer.
Overall design 10x Single-cell Transcriptome sequencing were used to obtain the characteristics of 2 TNBC samples , and 10x Spatial Transcriptome sequencing were used to obtain the characteristics of 4 TNBC samples.
Contributor(s) Qi F, Li J, Gao N, Qin W
Citation(s) 38730464
Submission date Dec 28, 2023
Last update date May 18, 2024
Contact name Qi Feng
Organization name Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Department Department of Oncology
Street address No. 197 Ruijin Second Road
City Shanghai
ZIP/Postal code 200000
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM7996201 TNBC tissue, replicate 1 [Spatial Transcriptome]
GSM7996202 TNBC tissue, replicate 2 [Spatial Transcriptome]
GSM7996203 TNBC tissue, replicate 3 [Spatial Transcriptome]
BioProject PRJNA1058423

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Supplementary file Size Download File type/resource
GSE252176_RAW.tar 191.1 Mb (http)(custom) TAR (of CSV, JPG, JSON, MTX, PNG, TSV)
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