NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE25193 Query DataSets for GSE25193
Status Public on Nov 09, 2010
Title Human fetal penile smooth muscle cells (hfPSCM): Control vs PCB mixtures treatments
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The effects exerted by three mixtures of Polychlorinated Biphenyls (PCB), one featuring dioxin-like (DL) and two featuring non dioxin-like (NDL) congeners, on human fetal corpora cavernosa cells representative of a major male endocrine-sensitive organ, have been evaluated by gene expression profiling. PCB congeners concentrations used were derived from human internal exposure data to explore the impact of the adult body burden on a fetal tissue. Cell exposure were performed for 72h mimicking a chronic exposure.
 
Overall design Experiment conditions: control, three treatments with PCB-Mix1, PCB-Mix2 or PCB-Mix3. Biological replicates: 3 control replicates, 3 replicates per treatment. Technical replica: 2 (dye swap) per biological replica. Direct comparison design (control vs treated samples) in 12/16 arrays (biological replicates 1 and 2); Loop design in 4/16 arrays (biological replicate 3).
 
Contributor(s) Tait S
Citation(s) 21334430
Submission date Nov 08, 2010
Last update date Feb 22, 2018
Contact name Sabrina Tait
E-mail(s) sabrina.tait@iss.it
Organization name Istituto Superiore di Sanità
Department Dpt. Veterinary Public Health and Food Safety
Lab Food And Veterinary Toxicology Unit
Street address Viale Regina Elena 299
City Rome
State/province Italy
ZIP/Postal code 00163
Country Italy
 
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (16)
GSM618837 hfPSMC_CTRLvsMix1_biolrep1_techrepl1
GSM618838 hfPSMC_CTRLvsMix2_biolrep1_techrepl1
GSM618839 hfPSMC_CTRLvsMix3_biolrep1_techrepl1
Relations
BioProject PRJNA134299

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE25193_RAW.tar 250.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap