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| Status |
Public on Jun 29, 2011 |
| Title |
Expression data from Saccharomyces cerevisiae strains deleted for different subunits of the THO/TREX complex |
| Platform organisms |
Schizosaccharomyces pombe; Saccharomyces cerevisiae |
| Sample organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by array
|
| Summary |
THO/TREX is a conserved nuclear complex that functions in mRNP biogenesis at the interface of transcription-RNA export with a key role in preventing transcription-associated genome instability.
We used microarrays to analyze the impact of different THO/TREX mutations on gene expression and found that THO-Sub2 deletions have a high functional impact on highly expressed, long and G+C-rich genes regardless of gene function.
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| Overall design |
S. cerevisiae strains were grown in YPAD liquid culture, total RNA was isolated and hybridized on Affymetrix microarrays.
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| Contributor(s) |
Gómez-González B, Tous C, Gaillard H, Marín A, Aguilera A |
| Citation(s) |
21701562 |
| Submission date |
Oct 19, 2010 |
| Last update date |
Feb 21, 2017 |
| Contact name |
Andrés Aguilera |
| Organization name |
CABIMER, Universidad de Sevilla
|
| Department |
Genome BIology
|
| Lab |
Genome Instability & Cancer
|
| Street address |
Av. Américo Vespucio 24
|
| City |
Seville |
| ZIP/Postal code |
41092 |
| Country |
Spain |
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| Platforms (1) |
| GPL2529 |
[Yeast_2] Affymetrix Yeast Genome 2.0 Array |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA132295 |
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