 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Feb 09, 2012 |
| Title |
Identification of target genes of tumor suppressor microRNAs in human cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To identify target genes of tumor suppressive microRNAs in human cancer, several cell lines (bladder cancer, prostate cancer, renal cell carcinoma, and head and neck squamous cell carcinoma) were subjected to Agilent whole genome microarrays. miR-517a, miR-218, miR-145, miR-1 and miR-874 function as tumor suppressors.
|
| |
|
| Overall design |
Human cancer cell lines (BOY, T24, A498, PC3, DU145, FaDu, SAS, HSC3, IMC3) were transfected with miRNAs (miR-517a, miR-218, miR-145, miR-1, miR-874). The miRNA-transfected human cancer cell lines were compared to control cell lines.
|
| |
|
| Contributor(s) |
Seki N |
| Citation(s) |
21378409, 21847129, 22378464, 22179486, 21304530 |
| |
| Submission date |
Oct 18, 2010 |
| Last update date |
Aug 19, 2019 |
| Contact name |
Naohiko Seki |
| E-mail(s) |
naoseki@faculty.chiba-u.jp
|
| Phone |
81-43-226-2971
|
| Fax |
81-43-227-3442
|
| Organization name |
Chiba University
|
| Department |
School of Medicine
|
| Lab |
Functional Genomics
|
| Street address |
1-8-1 Inohana,Chuo-ku
|
| City |
Chiba |
| State/province |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
| |
|
| Platforms (2) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
| GPL10332 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Feature Number version) |
|
| Samples (13)
|
| GSM610386 |
Identification of miR-517a target genes in bladder cancer, BOY |
| GSM610387 |
Identification of miR-517a target genes in bladder cancer, T24 |
| GSM610388 |
Identification of miR-218 target genes in bladder cancer, BOY |
| GSM610389 |
Identification of miR-218 target genes in bladder cancer, T24 |
| GSM610390 |
Identification of miR-1 target genes in bladder cancer, BOY |
| GSM610391 |
Identification of miR-1 target genes in bladder cancer, T24 |
| GSM610392 |
Identification of miR-1 target genes in renal cell carcinoma, A498 |
| GSM610393 |
Identification of miR-1 target genes in HNSCC, HSC3 |
| GSM610394 |
Identification of miR-1 target genes in HNSCC, FaDu |
| GSM610395 |
Identification of miR-874 target genes in HNSCC, IMC3 |
| GSM610396 |
Identification of miR-874 target genes in HNSCC, SAS |
| GSM610397 |
Identification of miR-145 target genes in prostate cancer, PC3 |
| GSM610398 |
Identification of miR-145 target genes in prostate cancer, DU145 |
|
| Relations |
| BioProject |
PRJNA132229 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE24782_RAW.tar |
206.4 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...