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| Status |
Public on Jan 30, 2024 |
| Title |
Transcriptomic analysis GM12878 Lymphoblastoid cell line (LCL) upon CRISPR knockout of the individual NF-κB transcription factor. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA-seq was used to characterize the NF-κB transcription factor -mediated regulation of B-cell genome wide target genes in Latency III GM12878 Lymphoblastoid cell upon stable CRISPR knockout of the individual NF-κB transcription factors.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data GM12878 Lymphoblastoid cell line (LCL) cells upon stable CRISPR knock out each of the five NF-κB transcription factor (p50,p52, RelB, cRel or RelA). GM12878 cells bearing a non-targeting control is used as the control
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| Contributor(s) |
Mitra B, Ma Y, Walsh M, Zhou Z, Beri N, Guo R, Murray-Nerger L, Gewurz BE |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 10, 2023 |
| Last update date |
Jan 30, 2024 |
| Contact name |
Bidisha Mitra |
| E-mail(s) |
eshaanimitra07@gmail.com, bmitra@bwh.harvard.edu
|
| Phone |
3172704973
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| Organization name |
Brigham and Women's Hospital
|
| Department |
Medicine
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| Lab |
Gewurz
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| Street address |
181 Longwood Avenue, 8th floor
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA1038795 |
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