 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Nov 15, 2023 |
| Title |
Combined anti-inflammatory and regenerative therapies rescue skeletal muscle after IRI through multi-pathway activation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Ten-week-old C57BL/6J mice were subjected to unilateral hind limb ischemia-reperfusion (I/R) injury by postural suspension method for 4 hours, and then treated with aspirin anti-inflammatory group and peptide functionalized hydrogel drug. RNA-seq analysis was then performed.
|
| |
|
| Overall design |
All mice were subjected to hindlimb suspension ischemia model. Then, three c57b6l mice were treated with aspirin for anti-inflammation(Asp group), three c57b6l mice were treated with peptide hydrogel combined with aspirin(Asp+Pep group), and three c57b6l mice were left untreated as controls(Ctrl group).
|
| |
|
| Contributor(s) |
Chen X, Jia J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 03, 2023 |
| Last update date |
Nov 15, 2023 |
| Contact name |
chen xingxing |
| E-mail(s) |
cxing998@outlook.com
|
| Phone |
18817358276
|
| Organization name |
Shanghai University
|
| Street address |
nanchen road 381
|
| City |
Shanghai |
| ZIP/Postal code |
201900 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (9)
|
| GSM7881540 |
Control, c57b6l mice,repeated1 [S9_2_S] |
| GSM7881541 |
Control, c57b6l mice,repeated2 [S9_4_S] |
| GSM7881542 |
Control, c57b6l mice,repeated3 [S9_5_S] |
| GSM7881543 |
Asp, c57b6l mice,repeated1 [S7_1_S] |
| GSM7881544 |
Asp, c57b6l mice,repeated2 [S7_3_S] |
| GSM7881545 |
Asp, c57b6l mice,repeated3 [S10_4_S] |
| GSM7881546 |
Asp+Pep, c57b6l mice,repeated1 [S8_1_S] |
| GSM7881547 |
Asp+Pep, c57b6l mice,repeated2 [S8_3_S] |
| GSM7881548 |
Asp+Pep, c57b6l mice,repeated3 [S8_5_S] |
|
| Relations |
| BioProject |
PRJNA1035445 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE246962_gene_sample_FPKM_with_symbol.txt.gz |
2.2 Mb |
(ftp)(http) |
TXT |
| GSE246962_gene_sample_count_with_symbol.txt.gz |
1.2 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
|
|
|
|
 |
Less...
More...