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Series GSE244706 Query DataSets for GSE244706
Status Public on Jun 21, 2024
Title Digital transformation of herbal medicine: Conversion to biological entity data using tonifying herbal medicine-induced transcriptome sequencing_HepG2_batchE
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary This study aimed to identify transcript expression induced by tonifying herbal medicines (THM) and modes of action (MOA) of THM in A549 cell line. For the production of THM-induced transcripts, tonifying herbal medicines water extract (THW) and tonifying herbal medicines ethanol extract (THE) were used.
 
Overall design Comparative gene expression profiling analysis of RNA-seq data for THW (500 ug/mL, 100 ug/mL, and 20 ug/mL, respectively), THE (500 ug/mL, 100 ug/mL, and 20 ug/mL, respectively), positive control (wortmannin 10uM), and vehicle control (2% DMSO). However, in extracts with IC20 of less than 500ug/mL, the concentration at IC20 and the concentration diluted to 1/5 and 1/25 of the IC20 concentration were used, respectively.
Please note that the RCM_tonifying_HepG2.txt contains processed data for all batch samples and the corresponding data column header is indicated in the sample description field.
 
Contributor(s) Park M
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Submission date Oct 05, 2023
Last update date Jun 21, 2024
Contact name Musun Park
E-mail(s) bmusun@kiom.re.kr
Organization name Korean Institute of Oriental Medicine
Street address 1672 Yuseong-daero, Yuseong-gu
City Daejeon
ZIP/Postal code 34054
Country South Korea
 
Platforms (1)
GPL30209 MGISEQ-2000RS (Homo sapiens)
Samples (30)
GSM7824587 HepG2_BatchE_Vehicle(DMSO)_rep1
GSM7824588 HepG2_BatchE_Vehicle(DMSO)_rep2
GSM7824589 HepG2_BatchE_Vehicle(DMSO)_rep3
This SubSeries is part of SuperSeries:
GSE244707 Digital transformation of herbal medicine: Conversion to biological entity data using tonifying herbal medicine-induced transcriptome sequencing_Tonifying_HepG2
Relations
BioProject PRJNA1024423

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE244706_RCM_tonifying_HepG2.txt.gz 10.5 Mb (ftp)(http) TXT
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Raw data are available in SRA
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