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| Status |
Public on May 01, 2024 |
| Title |
Immune cell transcriptional programs severe allergic airway inflammation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Innate and adpative immune cells play an integral role in asthma pathogenesis. We performed single cell RNA sequencing on CD45+ immune cells isolated from PBS or c-di-GMP + mixed allergen challenged mice.
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| Overall design |
CD45+ cell were isolated from the mouse lung following intranasal PBS or c-di-GMP + mixed allergen exposures 3X per week for 7 weeks. Two mouse lungs given the same treatments were pooled following digestion.
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| Contributor(s) |
Britt RD Jr, Walum J, Guerau-de-Arellano M, Amici S, Lewis BW |
| Citation missing |
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| |
| Submission date |
Oct 04, 2023 |
| Last update date |
May 01, 2024 |
| Contact name |
Rodney Britt |
| E-mail(s) |
Rodney.Britt@nationwidechildrens.org
|
| Phone |
6143556710
|
| Organization name |
Nationwide Children's Hospital
|
| Department |
Center for Perinatal Research
|
| Lab |
Britt Lab
|
| Street address |
575 Childrens Crossroad
|
| City |
Columbus |
| State/province |
Oh |
| ZIP/Postal code |
43215 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA1023958 |
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