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| Status |
Public on Sep 27, 2024 |
| Title |
Transcriptome analysis of lung neutrophils from mice infected with Mycobacterium tuberculosis |
| Organism |
Mus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Neutrophils are accumulated in mouse lungs following Mycobacterium tuberculosis infections. Increased influx of neutrophils is associated with increased susceptibility to disease, but the underlying mechanisms of neutrophil mediated Tuberculosis disease pathogenesis is poorly understood. To understand the transcriptomic differences between resistant (C57 BL/6) and susceptible (C3HeB/FeJ) mouse lung neutrophils, we sorted them at Day 29 post infection and analyzed them by bulk mRNA sequencing.
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| Overall design |
Bulk mRNA sequencing to study transcriptomic differences in neutrophils at Day 29 post infection with Mycobacterium tuberculosis HN878 from C57 BL/6 and C3HeB/FeJ mouse lungs.
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| Contributor(s) |
Sankar P, Mishra B, Bossardi Ramos R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 28, 2023 |
| Last update date |
Sep 27, 2024 |
| Contact name |
Ramon Bossardi Ramos |
| E-mail(s) |
bossarr@amc.edu
|
| Organization name |
Albany Medical College
|
| Department |
Department of Molecular and Cellular Physiology
|
| Lab |
Adam's Lab
|
| Street address |
43 New Scotland Avenue
|
| City |
Albany |
| State/province |
Ny |
| ZIP/Postal code |
12208 |
| Country |
USA |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1021944 |
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