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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 04, 2023 |
| Title |
BCG vaccination stimulates Integrated Organ Immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Bacille Calmette-Guérin (BCG) vaccination can confer non-specific protection against heterologous pathogens. However, the underlying mechanisms remain mysterious. We used scRNA-seq in this study to identify transcriptional changes in the immune and epithelial cells in the lungs following BCG vaccination in mice
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| Overall design |
Lung immune and epithelial cells were enriched by Fluorescence-activated cell sorting using respective cell markers and mixed with non-enriched fraction for scRNA-seq
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| Contributor(s) |
Lee A, Fang Z |
| Citation(s) |
38036767 |
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| Submission date |
Sep 26, 2023 |
| Last update date |
Dec 05, 2023 |
| Contact name |
Audrey Lee |
| E-mail(s) |
aleewq@stanford.edu
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| Organization name |
Stanford University
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| Street address |
240 Pasteur Dr. 1500 BMI
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| City |
Palo Alto |
| State/province |
CA |
| ZIP/Postal code |
94304 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA1021327 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE244126_RAW.tar |
203.3 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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