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| Status |
Public on Feb 16, 2024 |
| Title |
Microarray data of lenses with 2ME2 |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
The addition of 2ME2 (HIF-1 inhibitor) to rat model of galactose-induced cataract decreased opacity and therapeutic effect. Genes regulated by 2ME2 addition were identified by microarray analysis.
A total of 7 samples were analyzed: samples with no cataract (Control_Day4, Control_Day6), samples with cataract (Galactose-1, Galactose-2, Galactose-3), samples with decreased lens opacity (2ME2, 2ME2-2)
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| Overall design |
Genes whose expression increased from Control to Galactose and decreased from Galactose to 2ME2 were extracted.
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| Contributor(s) |
Takashima M, Nagaya M, Takamura Y, Inatani M, Oki M |
| Citation(s) |
38416732 |
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| Submission date |
Aug 10, 2023 |
| Last update date |
Mar 01, 2024 |
| Contact name |
Masaru Takashima |
| Organization name |
University of Fukui
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| Street address |
3-9-1 Bunkyo
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| City |
Fukui |
| ZIP/Postal code |
910-8507 |
| Country |
Japan |
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| Platforms (1) |
| GPL17117 |
[RaGene-2_0-st] Affymetrix Rat Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA1004317 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE240617_RAW.tar |
52.2 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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