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Status |
Public on Aug 02, 2023 |
Title |
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer [ATAC] |
Organism |
human gammaherpesvirus 4 |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
To investigate the EBV genome after Decitabine treatment by reduced representation bisulfite sequencing, ATAC-seq, and RNA-seq
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Overall design |
Two EBV positive gastric cancer cell lines were treated with decitabine for 1 and 3 days and ATAC-seq was performed
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Contributor(s) |
Tempera I, Leiberman PM |
Citation(s) |
37606370 |
|
Submission date |
Jul 31, 2023 |
Last update date |
Dec 07, 2023 |
Contact name |
Priyankara J Wickramasinghe |
E-mail(s) |
priyaw@wistar.org
|
Phone |
2154956837
|
Organization name |
The Wistar Institute
|
Department |
Bioinformatics
|
Lab |
Genomics
|
Street address |
3601 Spruce Street
|
City |
Philadelphia |
State/province |
PA |
ZIP/Postal code |
19104 |
Country |
USA |
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Platforms (1) |
GPL33481 |
Illumina NextSeq 500 (Human gammaherpesvirus 4) |
|
Samples (12)
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This SubSeries is part of SuperSeries: |
GSE239770 |
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer |
|
Relations |
BioProject |
PRJNA1000476 |