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Status |
Public on Dec 31, 2013 |
Title |
Comparative global transcriptomic profiling of mild and severe neurotrauma in an in vitro neuronal model |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Traumatic brain injury is one of the common cause of adult permanent disability. As its physio-pathological mechanism has yet to be elucidated, by adopting microarray technique we hope to decipher the novel signaling cascades involved, and if different severity of injury would induce any form of neuronal regeneration.
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Overall design |
Microarray was performed on 34 arrays on Illumina Rat Ref12V1 expression beadchips. 6 control samples were adopted as universal controls, and n=3 was used for each time-points (0h, 8h, 15h, 24h and 48h) for Mild neurotrauma and (8h, 15h, 24h and 48h) for Severe neurotrauma. Only one replicate is present for 0h Severe neurotrauma.
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Contributor(s) |
Cheung NS, Chen MJ, Peng ZF, Chung R |
Citation(s) |
21711447 |
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Submission date |
Aug 16, 2010 |
Last update date |
Jul 12, 2018 |
Contact name |
Minghui Jessica Chen |
Organization name |
Menzies Research Institute
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Department |
Neuroscience group
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Lab |
A/P Steve Cheung
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Street address |
Menzies Research Institute, University of Tasmania, Private Bag 24
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City |
Hobart |
State/province |
Tasmania |
ZIP/Postal code |
7001 |
Country |
Australia |
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Platforms (1) |
GPL8031 |
Illumina ratRef-12 v1.5.0.34 expression beadchip |
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Samples (34)
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Relations |
BioProject |
PRJNA130971 |