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Series GSE236246 Query DataSets for GSE236246
Status Public on Aug 07, 2024
Title DNA methylation arrays: The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Organism Mus musculus
Experiment type Methylation profiling by array
Summary To investigate how IFNγ treatment during early stages of reprogramming could affect DNA methylation levels and its link with X-chromosome reactivation, we analyzed 5mC and 5hmC levels in cells undergoing reprogramming, in the presence or absence of IFNγ treatment, using mouse DNA methylation arrays.
 
Overall design Mouse DNA methylation arrays for cells undergoing reprogramming at days 5 and 7, in the presence or absence of IFNγ. Analysis of 5mC and 5hmC levels.
Web link http://www.science.org/doi/10.1126/sciadv.adj8862
 
Contributor(s) Barrero M, Payer B, Sardina JL, López-Rubio AV, Lazarenkov A
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Submission date Jun 30, 2023
Last update date Aug 07, 2024
Contact name Mercedes Barrero
Organization name Centre for Genomic Regulation
Street address Dr. Aiguader, 88
City Barcelona
ZIP/Postal code 08003
Country Spain
 
Platforms (1)
GPL31950 Infinium MouseMethylation285 BeadChip
Samples (32)
GSM7520305 DNA methylation array - Day 5 iPSC control Rep1_BS_OX
GSM7520306 DNA methylation array - Day 5 iPSC control Rep1_BS
GSM7520307 DNA methylation array - Day 5 iPSC IFNg Rep1_BS_OX
This SubSeries is part of SuperSeries:
GSE236247 The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Relations
BioProject PRJNA989565

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE236246_DNA_methylation_beta_values.xlsx 118.2 Mb (ftp)(http) XLSX
GSE236246_RAW.tar 166.4 Mb (http)(custom) TAR (of IDAT)
Processed data are available on Series record
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