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| Status |
Public on Sep 20, 2023 |
| Title |
Identification of 5-methylcytosine associated genes in osteoarthritis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
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| Summary |
Our study aimed to identify common m5C features in OA. We identified we found 35828 m5C peaks and mapped up to 11720 annotated genes in OA samples, and we found 16259 m5C peaks and mapped up to 7504 annotated genes in normal samples, indicating an overall hypermethylated level in the OA cartilage.
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| Overall design |
We collected three OA knee cartilage tissues and three normal knee cartilage tissues to obtain the transcriptome-wide m5C modification profile of genes in OA by methylated RNA immunoprecipitation next-generation sequencing (MeRIP-seq).
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| Contributor(s) |
Yu Y, Lu S, Xu J |
| Citation(s) |
37700248 |
| |
| Submission date |
Jun 22, 2023 |
| Last update date |
Sep 20, 2023 |
| Contact name |
yang yu |
| E-mail(s) |
yuyang.1012@aliyun.com
|
| Organization name |
the First Affiliated Hospital of Zhengzhou University
|
| Department |
Department of orthopedics
|
| Street address |
jianshe road
|
| City |
zhengzhou |
| State/province |
henan province |
| ZIP/Postal code |
450000 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA986548 |
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